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==Crystal structure of Saccharomyces cerevisiae NUP192, residues 2 to 960 [ScNup192(2-960)]==
==Crystal structure of Saccharomyces cerevisiae NUP192, residues 2 to 960 [ScNup192(2-960)]==
<StructureSection load='4ifq' size='340' side='right' caption='[[4ifq]], [[Resolution|resolution]] 3.25&Aring;' scene=''>
<StructureSection load='4ifq' size='340' side='right'caption='[[4ifq]], [[Resolution|resolution]] 3.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ifq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IFQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IFQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ifq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IFQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IFQ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.25&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">J1216, NUP192, YJL039C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ifq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ifq OCA], [https://pdbe.org/4ifq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ifq RCSB], [https://www.ebi.ac.uk/pdbsum/4ifq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ifq ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ifq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ifq OCA], [http://pdbe.org/4ifq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ifq RCSB], [http://www.ebi.ac.uk/pdbsum/4ifq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ifq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NU192_YEAST NU192_YEAST]] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NUP192 is located to the NPC core at the nuclear membrane and is essential for de novo assembly of NPCs.<ref>PMID:10428845</ref> <ref>PMID:11121302</ref>
[https://www.uniprot.org/uniprot/NU192_YEAST NU192_YEAST] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NUP192 is located to the NPC core at the nuclear membrane and is essential for de novo assembly of NPCs.<ref>PMID:10428845</ref> <ref>PMID:11121302</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Nucleoporin|Nucleoporin]]
*[[Nucleoporin 3D structures|Nucleoporin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Baker's yeast]]
[[Category: Large Structures]]
[[Category: Almo, S C]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: NPCXstals, Nucleocytoplasmic Transport:.a Target for Cellular Control]]
[[Category: Almo SC]]
[[Category: Structural genomic]]
[[Category: Sampathkumar P]]
[[Category: Sampathkumar, P]]
[[Category: Alpha solenoid-like]]
[[Category: Npc]]
[[Category: Npcxstal]]
[[Category: Nuclear pore complex component]]
[[Category: Nucleocytoplasmic transport: a target for cellular control]]
[[Category: Nucleoporin]]
[[Category: Nup188]]
[[Category: Nup192]]
[[Category: Nysgrc]]
[[Category: Protein transport]]
[[Category: Psi-biology]]
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