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==X-RAY STRUCTURE OF HUMAN RELAXIN AT 1.5 ANGSTROMS. COMPARISON TO INSULIN AND IMPLICATIONS FOR RECEPTOR BINDING DETERMINANTS==
==X-RAY STRUCTURE OF HUMAN RELAXIN AT 1.5 ANGSTROMS. COMPARISON TO INSULIN AND IMPLICATIONS FOR RECEPTOR BINDING DETERMINANTS==
<StructureSection load='6rlx' size='340' side='right' caption='[[6rlx]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='6rlx' size='340' side='right'caption='[[6rlx]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6rlx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RLX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RLX FirstGlance]. <br>
<table><tr><td colspan='2'>[[6rlx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RLX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RLX FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rlx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rlx OCA], [http://pdbe.org/6rlx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rlx RCSB], [http://www.ebi.ac.uk/pdbsum/6rlx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rlx ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rlx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rlx OCA], [https://pdbe.org/6rlx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rlx RCSB], [https://www.ebi.ac.uk/pdbsum/6rlx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rlx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/REL2_HUMAN REL2_HUMAN]] Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.  
[https://www.uniprot.org/uniprot/REL2_HUMAN REL2_HUMAN] Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Eigenbrot, C]]
[[Category: Large Structures]]
[[Category: Kossiakoff, A A]]
[[Category: Eigenbrot C]]
[[Category: Randal, M]]
[[Category: Kossiakoff AA]]
[[Category: Randal M]]
Retrieved from "https://proteopedia.org/6rlx"