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==Crystal structure of domain I of the envelope glycoprotein ectodomain from dengue virus serotype 4 in complex with the fab fragment of the chimpanzee monoclonal antibody 5H2==
==Crystal structure of domain I of the envelope glycoprotein ectodomain from dengue virus serotype 4 in complex with the fab fragment of the chimpanzee monoclonal antibody 5H2==
<StructureSection load='3uc0' size='340' side='right' caption='[[3uc0]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
<StructureSection load='3uc0' size='340' side='right'caption='[[3uc0]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3uc0]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Chimpansee_troglodytes Chimpansee troglodytes] and [http://en.wikipedia.org/wiki/Dengue_virus_4 Dengue virus 4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UC0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UC0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3uc0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_4 Dengue virus 4] and [https://en.wikipedia.org/wiki/Pan_troglodytes Pan troglodytes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UC0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.71&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3uaj|3uaj]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">envelope ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11070 Dengue virus 4])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uc0 OCA], [https://pdbe.org/3uc0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uc0 RCSB], [https://www.ebi.ac.uk/pdbsum/3uc0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uc0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uc0 OCA], [http://pdbe.org/3uc0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3uc0 RCSB], [http://www.ebi.ac.uk/pdbsum/3uc0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3uc0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q91AI1_9FLAV Q91AI1_9FLAV]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[3D structures of monoclonal antibody|3D structures of monoclonal antibody]]
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chimpansee troglodytes]]
[[Category: Dengue virus 4]]
[[Category: Dengue virus 4]]
[[Category: Cockburn, J J.B]]
[[Category: Large Structures]]
[[Category: Navarro-Sanchez, M E]]
[[Category: Pan troglodytes]]
[[Category: Rey, F A]]
[[Category: Cockburn JJB]]
[[Category: Stura, E A]]
[[Category: Navarro-Sanchez ME]]
[[Category: Dengue antibody membrane fusion]]
[[Category: Rey FA]]
[[Category: Viral protein-immune system complex]]
[[Category: Stura EA]]
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