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==Structural basis for zymogen activation and substrate binding of transglutaminase from Streptomyces mobaraense==
==Structural basis for zymogen activation and substrate binding of transglutaminase from Streptomyces mobaraense==
<StructureSection load='3iu0' size='340' side='right' caption='[[3iu0]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3iu0' size='340' side='right'caption='[[3iu0]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3iu0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"streptomyces_mobaraensis"_nagatsu_and_suzuki_1963 "streptomyces mobaraensis" nagatsu and suzuki 1963]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IU0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IU0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3iu0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_mobaraensis Streptomyces mobaraensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IU0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IU0 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1iu4|1iu4]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-glutamine_gamma-glutamyltransferase Protein-glutamine gamma-glutamyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.13 2.3.2.13] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iu0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iu0 OCA], [https://pdbe.org/3iu0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iu0 RCSB], [https://www.ebi.ac.uk/pdbsum/3iu0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iu0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iu0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iu0 OCA], [http://pdbe.org/3iu0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iu0 RCSB], [http://www.ebi.ac.uk/pdbsum/3iu0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3iu0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TGAS_STRMB TGAS_STRMB]] Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.  
[https://www.uniprot.org/uniprot/TGAS_STRMB TGAS_STRMB] Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iu/3iu0_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iu/3iu0_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Streptomyces mobaraensis nagatsu and suzuki 1963]]
[[Category: Large Structures]]
[[Category: Protein-glutamine gamma-glutamyltransferase]]
[[Category: Streptomyces mobaraensis]]
[[Category: Li, T T]]
[[Category: Li TT]]
[[Category: Acyltransferase]]
[[Category: Cross-linking]]
[[Category: Mtgase]]
[[Category: Pro-enzyme]]
[[Category: Transferase]]
[[Category: Zymogen]]

Latest revision as of 16:03, 1 November 2023

Structural basis for zymogen activation and substrate binding of transglutaminase from Streptomyces mobaraense

3iu0, resolution 1.90Å

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