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==X-Ray Crystal Structure of the passenger domain of Plasmid encoded toxin, an Autrotansporter Enterotoxin from enteroaggregative Escherichia coli (EAEC)==
==X-Ray Crystal Structure of the passenger domain of Plasmid encoded toxin, an Autrotansporter Enterotoxin from enteroaggregative Escherichia coli (EAEC)==
<StructureSection load='4om9' size='340' side='right' caption='[[4om9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='4om9' size='340' side='right'caption='[[4om9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4om9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Eaec_042 Eaec 042]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OM9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OM9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4om9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_042 Escherichia coli 042]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OM9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OM9 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sze|3sze]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EC042_pAA035, pet ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=216592 EAEC 042])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4om9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4om9 OCA], [https://pdbe.org/4om9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4om9 RCSB], [https://www.ebi.ac.uk/pdbsum/4om9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4om9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4om9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4om9 OCA], [http://pdbe.org/4om9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4om9 RCSB], [http://www.ebi.ac.uk/pdbsum/4om9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4om9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PET_ECO44 PET_ECO44]] Serine protease with enterotoxic and cytotoxic activity. Internalization into the host cell is required for the induction of cytopathic effects. However, the serine activity is not necessary for secretion and internalization into the host cell.<ref>PMID:9632580</ref> <ref>PMID:10225873</ref> <ref>PMID:10496914</ref> <ref>PMID:11160002</ref>
[https://www.uniprot.org/uniprot/PET_ECO44 PET_ECO44] Serine protease with enterotoxic and cytotoxic activity. Internalization into the host cell is required for the induction of cytopathic effects. However, the serine activity is not necessary for secretion and internalization into the host cell.<ref>PMID:9632580</ref> <ref>PMID:10225873</ref> <ref>PMID:10496914</ref> <ref>PMID:11160002</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Eaec 042]]
[[Category: Escherichia coli 042]]
[[Category: Eslava-Campos, C A]]
[[Category: Large Structures]]
[[Category: Fromme, P]]
[[Category: Arreguin-Espinosa de Los Monteros RA]]
[[Category: Fromme, R]]
[[Category: Eslava-Campos CA]]
[[Category: Hernandez-Chinas, U]]
[[Category: Fromme P]]
[[Category: Mendoza-Hernandez, G]]
[[Category: Fromme R]]
[[Category: Meza-Aguilar, J D]]
[[Category: Hernandez-Chinas U]]
[[Category: Monteros, R A.Arreguin-Espinosa de Los]]
[[Category: Mendoza-Hernandez G]]
[[Category: Torres-Larios, A]]
[[Category: Meza-Aguilar JD]]
[[Category: Alpha-fodrin]]
[[Category: Torres-Larios A]]
[[Category: Beta-helix]]
[[Category: Eaec]]
[[Category: Hydrolase]]
[[Category: Peptidase]]