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==I-SceI complexed with C/G+4 DNA substrate==
==I-SceI complexed with C/G+4 DNA substrate==
<StructureSection load='3ool' size='340' side='right' caption='[[3ool]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='3ool' size='340' side='right'caption='[[3ool]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ool]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OOL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OOL FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ool]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OOL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OOL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3oor|3oor]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SceI,omega ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ool FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ool OCA], [https://pdbe.org/3ool PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ool RCSB], [https://www.ebi.ac.uk/pdbsum/3ool PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ool ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ool FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ool OCA], [http://pdbe.org/3ool PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ool RCSB], [http://www.ebi.ac.uk/pdbsum/3ool PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ool ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SCE1_YEAST SCE1_YEAST]] Mitochondrial DNA endonuclease involved in intron homing. It introduces a specific double-strand break in the DNA of the 21S rRNA gene and thus mediates the insertion of an intron, containing its own coding sequence (group I intron), into an intronless gene. Specifically recognizes and cleaves the sequence 5'-TAGGGATAACAGGGTAAT-3'.  
[https://www.uniprot.org/uniprot/SCE1_YEAST SCE1_YEAST] Mitochondrial DNA endonuclease involved in intron homing. It introduces a specific double-strand break in the DNA of the 21S rRNA gene and thus mediates the insertion of an intron, containing its own coding sequence (group I intron), into an intronless gene. Specifically recognizes and cleaves the sequence 5'-TAGGGATAACAGGGTAAT-3'.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Endonuclease|Endonuclease]]
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Chen, J-H]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Gimble, F S]]
[[Category: Chen J-H]]
[[Category: Golden, B L]]
[[Category: Gimble FS]]
[[Category: Joshi, R]]
[[Category: Golden BL]]
[[Category: Homing endonuclease]]
[[Category: Joshi R]]
[[Category: Hydrolase-dna complex]]
[[Category: Intron homing]]
[[Category: Laglidadg]]
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