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==Crystal structure of YagE, a prophage protein from E. coli K12 in complex with KDGal==
==Crystal structure of YagE, a prophage protein from E. coli K12 in complex with KDGal==
<StructureSection load='3nev' size='340' side='right' caption='[[3nev]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
<StructureSection load='3nev' size='340' side='right'caption='[[3nev]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3nev]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NEV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NEV FirstGlance]. <br>
<table><tr><td colspan='2'>[[3nev]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NEV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NEV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=RSH:3-DEOXY-D-LYXO-HEXONIC+ACID'>RSH</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.19&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2v8z|2v8z]], [[2v9d|2v9d]], [[3n2x|3n2x]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=RSH:3-DEOXY-D-LYXO-HEXONIC+ACID'>RSH</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b0268, JW0261, yagE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nev OCA], [https://pdbe.org/3nev PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nev RCSB], [https://www.ebi.ac.uk/pdbsum/3nev PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nev ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nev OCA], [http://pdbe.org/3nev PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nev RCSB], [http://www.ebi.ac.uk/pdbsum/3nev PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nev ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/YAGE_ECOLI YAGE_ECOLI]] Catalyzes the formation of 2-keto-3-deoxy-galactonate (KDGal) from pyruvate and glyceraldehyde. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin.  
[https://www.uniprot.org/uniprot/YAGE_ECOLI YAGE_ECOLI] Catalyzes the formation of 2-keto-3-deoxy-galactonate (KDGal) from pyruvate and glyceraldehyde. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Bhaskar, V]]
[[Category: Large Structures]]
[[Category: Krishnaswamy, S]]
[[Category: Bhaskar V]]
[[Category: Kumar, P M]]
[[Category: Krishnaswamy S]]
[[Category: Manicka, S]]
[[Category: Kumar PM]]
[[Category: Aldolase]]
[[Category: Manicka S]]
[[Category: Lyase]]
[[Category: Protein-ligand complex]]
[[Category: Tim barrel]]
Retrieved from "https://proteopedia.org/3nev"