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==A thiazolyl-mannoside bound to FimH, orthorhombic space group==
==A thiazolyl-mannoside bound to FimH, orthorhombic space group==
<StructureSection load='3zl2' size='340' side='right' caption='[[3zl2]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
<StructureSection load='3zl2' size='340' side='right'caption='[[3zl2]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3zl2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_j96 Escherichia coli j96]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZL2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZL2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3zl2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_J96 Escherichia coli J96]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZL2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZL2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BWG:N-{5-[(1R)-1-HYDROXYETHYL]-1,3-THIAZOL-2-YL}-ALPHA-D-MANNOPYRANOSYLAMINE'>BWG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.251&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zl1|3zl1]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BWG:N-{5-[(1R)-1-HYDROXYETHYL]-1,3-THIAZOL-2-YL}-ALPHA-D-MANNOPYRANOSYLAMINE'>BWG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zl2 OCA], [http://pdbe.org/3zl2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zl2 RCSB], [http://www.ebi.ac.uk/pdbsum/3zl2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zl2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zl2 OCA], [https://pdbe.org/3zl2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zl2 RCSB], [https://www.ebi.ac.uk/pdbsum/3zl2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zl2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.  
[https://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 3zl2" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3zl2" style="background-color:#fffaf0;"></div>
==See Also==
*[[Adhesin 3D structures|Adhesin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Escherichia coli j96]]
[[Category: Escherichia coli J96]]
[[Category: Bilyy, R O]]
[[Category: Large Structures]]
[[Category: Bouckaert, J]]
[[Category: Bilyy RO]]
[[Category: Brument, S]]
[[Category: Bouckaert J]]
[[Category: Chalopin, T]]
[[Category: Brument S]]
[[Category: Darfeuille-Michaud, A]]
[[Category: Chalopin T]]
[[Category: Deniaud, D]]
[[Category: Darfeuille-Michaud A]]
[[Category: Dumych, T I]]
[[Category: Deniaud D]]
[[Category: Gouin, S G]]
[[Category: Dumych TI]]
[[Category: Guerardel, Y]]
[[Category: Gouin SG]]
[[Category: Moreau, N]]
[[Category: Guerardel Y]]
[[Category: Roos, G]]
[[Category: Moreau N]]
[[Category: Sivignon, A]]
[[Category: Roos G]]
[[Category: Cell adhesion]]
[[Category: Sivignon A]]
[[Category: Crohn's disease]]
[[Category: Immunoglobulin]]
[[Category: Thiazole]]
[[Category: Type-1 fimbriae]]
Retrieved from "https://proteopedia.org/3zl2"