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==Crystal Structutre of Thiobacillus thioparus THI115 Carbonyl Sulfide Hydrolase / Thiocyanate complex==
==Crystal Structutre of Thiobacillus thioparus THI115 Carbonyl Sulfide Hydrolase / Thiocyanate complex==
<StructureSection load='3vrk' size='340' side='right' caption='[[3vrk]], [[Resolution|resolution]] 1.33&Aring;' scene=''>
<StructureSection load='3vrk' size='340' side='right'caption='[[3vrk]], [[Resolution|resolution]] 1.33&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3vrk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_thiocyanoxidans"_happold_and_key_1937 "bacterium thiocyanoxidans" happold and key 1937]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VRK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VRK FirstGlance]. <br>
<table><tr><td colspan='2'>[[3vrk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thiobacillus_thioparus Thiobacillus thioparus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VRK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VRK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.33&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3vqj|3vqj]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cos ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=931 "Bacterium thiocyanoxidans" Happold and Key 1937])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vrk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vrk OCA], [https://pdbe.org/3vrk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vrk RCSB], [https://www.ebi.ac.uk/pdbsum/3vrk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vrk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vrk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vrk OCA], [http://pdbe.org/3vrk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vrk RCSB], [http://www.ebi.ac.uk/pdbsum/3vrk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3vrk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/COSH_THITI COSH_THITI] Catalyzes the degradation of carbonyl sulfide (COS) to hydrogen sulfide and CO(2) (PubMed:23406161, PubMed:29199215). May function as one of the microbial sinks for ambient COS, which is an atmospheric trace gas leading to sulfate aerosol formation, thereby participating in the global radiation balance and ozone chemistry (PubMed:23406161). Shows little CO(2) hydration activity and poor carbon disulfide (CS(2)) hydrolysis activity (PubMed:23406161).<ref>PMID:23406161</ref> <ref>PMID:29199215</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacterium thiocyanoxidans happold and key 1937]]
[[Category: Large Structures]]
[[Category: Katayama, Y]]
[[Category: Thiobacillus thioparus]]
[[Category: Noguchi, K]]
[[Category: Katayama Y]]
[[Category: Odaka, M]]
[[Category: Noguchi K]]
[[Category: Ogawa, T]]
[[Category: Odaka M]]
[[Category: Ohtaki, A]]
[[Category: Ogawa T]]
[[Category: Yohda, M]]
[[Category: Ohtaki A]]
[[Category: Alpha/beta-fold]]
[[Category: Yohda M]]
[[Category: Homotetramer]]
[[Category: Hydrolase]]
Retrieved from "https://proteopedia.org/3vrk"