3qr2: Difference between revisions

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==Wild type CD147 Ig0 domain==
==Wild type CD147 Ig0 domain==
<StructureSection load='3qr2' size='340' side='right' caption='[[3qr2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='3qr2' size='340' side='right'caption='[[3qr2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3qr2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QR2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3qr2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QR2 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qqn|3qqn]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BSG, UNQ6505/PRO21383 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qr2 OCA], [https://pdbe.org/3qr2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qr2 RCSB], [https://www.ebi.ac.uk/pdbsum/3qr2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qr2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qr2 OCA], [http://pdbe.org/3qr2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3qr2 RCSB], [http://www.ebi.ac.uk/pdbsum/3qr2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3qr2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BASI_HUMAN BASI_HUMAN]] Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.<ref>PMID:17127621</ref>
[https://www.uniprot.org/uniprot/BASI_HUMAN BASI_HUMAN] Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.<ref>PMID:17127621</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Armstrong, G S]]
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Armstrong GS]]
[[Category: Eisenmesser, E Z]]
[[Category: Eisenmesser EZ]]
[[Category: Isern, N G]]
[[Category: Isern NG]]
[[Category: Kieft, J S]]
[[Category: Kieft JS]]
[[Category: Redzic, J S]]
[[Category: Redzic JS]]
[[Category: Beta sheet]]
[[Category: Bsgc]]
[[Category: Cd147]]
[[Category: Cell adhesion]]
[[Category: Emmprin]]
[[Category: Immunoglobulin-like domain]]