3uv6: Difference between revisions
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==Ec_IspH in complex with 4-hydroxybutyl diphosphate (1301)== | ==Ec_IspH in complex with 4-hydroxybutyl diphosphate (1301)== | ||
<StructureSection load='3uv6' size='340' side='right' caption='[[3uv6]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='3uv6' size='340' side='right'caption='[[3uv6]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3uv6]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3uv6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UV6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UV6 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0CH:4-HYDROXYBUTYL+TRIHYDROGEN+DIPHOSPHATE'>0CH</scene></td></tr> | |||
<tr id=' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uv6 OCA], [https://pdbe.org/3uv6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uv6 RCSB], [https://www.ebi.ac.uk/pdbsum/3uv6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uv6 ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ISPH_ECOLI ISPH_ECOLI] Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Is also involved in penicillin tolerance and control of the stringent response. Seems to directly or indirectly interact with RelA to maintain it in an inactive form during normal growth.<ref>PMID:19569147</ref> <ref>PMID:20080550</ref> <ref>PMID:22137895</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 23: | Line 21: | ||
==See Also== | ==See Also== | ||
*[[4-hydroxy-3-methylbut-2-enyl diphosphate reductase|4-hydroxy-3-methylbut-2-enyl diphosphate reductase]] | *[[4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3D structures|4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli K-12]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Bacher | [[Category: Bacher A]] | ||
[[Category: Eisenreich | [[Category: Eisenreich W]] | ||
[[Category: Groll | [[Category: Groll M]] | ||
[[Category: Oldfield | [[Category: Oldfield E]] | ||
[[Category: Schulz | [[Category: Schulz C]] | ||
[[Category: Span | [[Category: Span I]] | ||
[[Category: Wang | [[Category: Wang K]] | ||
[[Category: Wang | [[Category: Wang W]] | ||
[[Category: Zhang | [[Category: Zhang Y]] | ||
