1mjf: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(13 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1mjf.gif|left|200px]]


{{Structure
==PUTATIVE SPERMIDINE SYNTHETASE FROM PYROCOCCUS FURIOSUS PFU-132382==
|PDB= 1mjf |SIZE=350|CAPTION= <scene name='initialview01'>1mjf</scene>, resolution 1.798&Aring;
<StructureSection load='1mjf' size='340' side='right'caption='[[1mjf]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1mjf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MJF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MJF FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Spermidine_synthase Spermidine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.16 2.5.1.16] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.798&#8491;</td></tr>
|GENE=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mjf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mjf OCA], [https://pdbe.org/1mjf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mjf RCSB], [https://www.ebi.ac.uk/pdbsum/1mjf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mjf ProSAT], [https://www.topsan.org/Proteins/SECSG/1mjf TOPSAN]</span></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK00811 PRK00811]</span>
</table>
|RELATEDENTRY=[[1inl|1INL]]
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mjf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mjf OCA], [http://www.ebi.ac.uk/pdbsum/1mjf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1mjf RCSB]</span>
[https://www.uniprot.org/uniprot/SPEE_PYRFU SPEE_PYRFU] Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high-temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to various amine acceptors such as cadaverine, putrescine, agmatine, 1,3-diaminopropane, and sym-nor-spermidine. The reaction involves a nucleophilic attack on the C-3 methylene of the propylamine moiety adjacent to the positively charged sulfur of decarboxy-AdoMet.<ref>PMID:17545282</ref>
}}
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mj/1mjf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mjf ConSurf].
<div style="clear:both"></div>


'''PUTATIVE SPERMIDINE SYNTHETASE FROM PYROCOCCUS FURIOSUS PFU-132382'''
==See Also==
 
*[[Spermidine synthase 3D structures|Spermidine synthase 3D structures]]
 
== References ==
==About this Structure==
<references/>
1MJF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MJF OCA].
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
[[Category: Single protein]]
[[Category: Spermidine synthase]]
[[Category: SECSG, Southeast Collaboratory for Structural Genomics.]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: pyrococcus furiosus]]
[[Category: secsg]]
[[Category: southeast collaboratory for structural genomic]]
[[Category: spermidine synthetase]]
[[Category: structural genomic]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:16:47 2008''
Retrieved from "https://proteopedia.org/1mjf"