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==Crystal Structure of Glycogen Phosphorylase DK3 complex==
==Crystal Structure of Glycogen Phosphorylase DK3 complex==
<StructureSection load='3l7b' size='340' side='right' caption='[[3l7b]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3l7b' size='340' side='right'caption='[[3l7b]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3l7b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L7B FirstGlance]. <br>
<table><tr><td colspan='2'>[[3l7b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L7B FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DKZ:4-AMINO-1-(3-DEOXY-3-FLUORO-BETA-D-GLUCOPYRANOSYL)PYRIMIDIN-2(1H)-ONE'>DKZ</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DKZ:4-AMINO-1-(3-DEOXY-3-FLUORO-BETA-D-GLUCOPYRANOSYL)PYRIMIDIN-2(1H)-ONE'>DKZ</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3l79|3l79]], [[3l7a|3l7a]], [[3l7c|3l7c]], [[3l7d|3l7d]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l7b OCA], [https://pdbe.org/3l7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l7b RCSB], [https://www.ebi.ac.uk/pdbsum/3l7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l7b ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphorylase Phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.1 2.4.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l7b OCA], [http://pdbe.org/3l7b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3l7b RCSB], [http://www.ebi.ac.uk/pdbsum/3l7b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3l7b ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PYGM_RABIT PYGM_RABIT]] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.  
[https://www.uniprot.org/uniprot/PYGM_RABIT PYGM_RABIT] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Glycogen Phosphorylase|Glycogen Phosphorylase]]
*[[Glycogen phosphorylase 3D structures|Glycogen phosphorylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Phosphorylase]]
[[Category: Drakou C]]
[[Category: Drakou, C]]
[[Category: Hayes JM]]
[[Category: Hayes, J M]]
[[Category: Lamprakis C]]
[[Category: Lamprakis, C]]
[[Category: Leonidas DD]]
[[Category: Leonidas, D D]]
[[Category: Skamnaki V]]
[[Category: Skamnaki, V]]
[[Category: Tsirkone VG]]
[[Category: Tsirkone, V G]]
[[Category: Zographos SE]]
[[Category: Zographos, S E]]
[[Category: Allosteric enzyme]]
[[Category: Carbohydrate metabolism]]
[[Category: Glycogen metabolism]]
[[Category: Glycogenolysis]]
[[Category: Glycosyltransferase]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphorylation]]
[[Category: Pyridoxal phosphate]]
[[Category: Transferase]]
[[Category: Type 2 diabetes]]
Retrieved from "https://proteopedia.org/3l7b"