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==Crystal structure of CpxAHDC (orthorhombic form 1)==
==Crystal structure of CpxAHDC (orthorhombic form 1)==
<StructureSection load='4biu' size='340' side='right' caption='[[4biu]], [[Resolution|resolution]] 3.65&Aring;' scene=''>
<StructureSection load='4biu' size='340' side='right'caption='[[4biu]], [[Resolution|resolution]] 3.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4biu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BIU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BIU FirstGlance]. <br>
<table><tr><td colspan='2'>[[4biu]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BIU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BIU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.65&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4biv|4biv]], [[4biw|4biw]], [[4bix|4bix]], [[4biy|4biy]], [[4biz|4biz]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4biu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4biu OCA], [https://pdbe.org/4biu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4biu RCSB], [https://www.ebi.ac.uk/pdbsum/4biu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4biu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4biu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4biu OCA], [http://pdbe.org/4biu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4biu RCSB], [http://www.ebi.ac.uk/pdbsum/4biu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4biu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CPXA_ECOLI CPXA_ECOLI]] This protein is involved in several diverse cellular processes, such as the functioning of acetohydroxyacid synthetase I, in the biosynthesis of isoleucine and valine, the TraJ protein activation activity for tra gene expression in F plasmid, and the synthesis, translocation, or stability of cell envelope proteins. Activates CpxR by phosphorylation.  
[https://www.uniprot.org/uniprot/CPXA_ECOLI CPXA_ECOLI] This protein is involved in several diverse cellular processes, such as the functioning of acetohydroxyacid synthetase I, in the biosynthesis of isoleucine and valine, the TraJ protein activation activity for tra gene expression in F plasmid, and the synthesis, translocation, or stability of cell envelope proteins. Activates CpxR by phosphorylation.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Histidine kinase]]
[[Category: Large Structures]]
[[Category: Alzari, P M]]
[[Category: Alzari PM]]
[[Category: Betton, J M]]
[[Category: Betton JM]]
[[Category: Mechaly, A E]]
[[Category: Mechaly AE]]
[[Category: Sassoon, N]]
[[Category: Sassoon N]]
[[Category: Signal transduction]]
[[Category: Transferase]]
[[Category: Two-components system]]
Retrieved from "https://proteopedia.org/4biu"