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==Crystal structure of YycF DNA-binding domain from Staphylococcus aureus==
==Crystal structure of YycF DNA-binding domain from Staphylococcus aureus==
<StructureSection load='2zxj' size='340' side='right' caption='[[2zxj]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
<StructureSection load='2zxj' size='340' side='right'caption='[[2zxj]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2zxj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2z9m 2z9m]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZXJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2zxj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2z9m 2z9m]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZXJ FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yycF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.87&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zxj OCA], [http://pdbe.org/2zxj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zxj RCSB], [http://www.ebi.ac.uk/pdbsum/2zxj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zxj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zxj OCA], [https://pdbe.org/2zxj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zxj RCSB], [https://www.ebi.ac.uk/pdbsum/2zxj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zxj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/WALR_STAAU WALR_STAAU]] Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism (By similarity).  
[https://www.uniprot.org/uniprot/WALR_STAAU WALR_STAAU] Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zx/2zxj_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zx/2zxj_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
*[[Response regulator|Response regulator]]
*[[Response regulator 3D structure|Response regulator 3D structure]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Doi, A]]
[[Category: Large Structures]]
[[Category: Okajima, T]]
[[Category: Staphylococcus aureus]]
[[Category: Utsumi, R]]
[[Category: Doi A]]
[[Category: Activator]]
[[Category: Okajima T]]
[[Category: Dna-binding]]
[[Category: Utsumi R]]
[[Category: Dna-binding domain]]
[[Category: Helix-turn-helix motif]]
[[Category: Phosphoprotein]]
[[Category: Response regulator]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcriptional regulation]]
[[Category: Two-component regulatory system]]
[[Category: Two-component system]]
[[Category: Yycg]]

Latest revision as of 14:01, 1 November 2023

Crystal structure of YycF DNA-binding domain from Staphylococcus aureus

2zxj, resolution 1.87Å

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