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==THE CRYSTAL STRUCTURE OF IM2 IN COMPLEX WITH COLICIN E9 DNASE==
==The crystal structure of Im2 in complex with colicin E9 DNase==
<StructureSection load='2wpt' size='340' side='right' caption='[[2wpt]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
<StructureSection load='2wpt' size='340' side='right'caption='[[2wpt]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wpt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WPT FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wpt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WPT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ivz|2ivz]], [[1v14|1v14]], [[2vlo|2vlo]], [[1fsj|1fsj]], [[2vlp|2vlp]], [[2vln|2vln]], [[1v15|1v15]], [[1bxi|1bxi]], [[1v13|1v13]], [[2vlq|2vlq]], [[1emv|1emv]], [[1fr2|1fr2]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wpt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpt OCA], [http://pdbe.org/2wpt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wpt RCSB], [http://www.ebi.ac.uk/pdbsum/2wpt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wpt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wpt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpt OCA], [https://pdbe.org/2wpt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wpt RCSB], [https://www.ebi.ac.uk/pdbsum/2wpt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wpt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/IMM2_ECOLX IMM2_ECOLX]] This protein is able to protect a cell, which harbors the plasmid ColE2 encoding colicin E2, against colicin E2.  
[https://www.uniprot.org/uniprot/IMM2_ECOLX IMM2_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE2 encoding colicin E2, against colicin E2.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wp/2wpt_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wp/2wpt_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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==See Also==
==See Also==
*[[Colicin|Colicin]]
*[[Colicin 3D structures|Colicin 3D structures]]
*[[Colicin Immunity Protein|Colicin Immunity Protein]]
*[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Baker, D]]
[[Category: Large Structures]]
[[Category: Boetzel, R]]
[[Category: Baker D]]
[[Category: Fleishman, S J]]
[[Category: Boetzel R]]
[[Category: Kleanthous, C]]
[[Category: Fleishman SJ]]
[[Category: Macdonald, C J]]
[[Category: Kleanthous C]]
[[Category: Meenan, N A]]
[[Category: Macdonald CJ]]
[[Category: Moore, G R]]
[[Category: Meenan NA]]
[[Category: Sharma, A]]
[[Category: Moore GR]]
[[Category: Antibiotic]]
[[Category: Sharma A]]
[[Category: Antimicrobial]]
[[Category: Bacteriocin immunity]]
[[Category: Endonuclease]]
[[Category: Hydrolase]]
[[Category: Immune system]]
[[Category: Nuclease]]