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==Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Caribbean Sea anemone Stichodactyla helianthus in complex with bovine chymotrypsin==
==Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Caribbean Sea anemone Stichodactyla helianthus in complex with bovine chymotrypsin==
<StructureSection load='3t62' size='340' side='right' caption='[[3t62]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3t62' size='340' side='right'caption='[[3t62]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3t62]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Carribean_sea_anemone Carribean sea anemone]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T62 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T62 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3t62]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Stichodactyla_helianthus Stichodactyla helianthus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T62 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chymotrypsin Chymotrypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.1 3.4.21.1] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t62 OCA], [http://pdbe.org/3t62 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3t62 RCSB], [http://www.ebi.ac.uk/pdbsum/3t62 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3t62 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t62 OCA], [https://pdbe.org/3t62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t62 RCSB], [https://www.ebi.ac.uk/pdbsum/3t62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t62 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ISH1_STOHE ISH1_STOHE]] Active against serine, cysteine, and aspartic proteinases. Can bind vertebrate trypsin and chymotrypsin.<ref>PMID:9027993</ref> <ref>PMID:22975140</ref> 
[https://www.uniprot.org/uniprot/CTRA_BOVIN CTRA_BOVIN]  


==See Also==
==See Also==
*[[Chymotrypsin|Chymotrypsin]]
*[[Chymotrypsin 3D structures|Chymotrypsin 3D structures]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Carribean sea anemone]]
[[Category: Large Structures]]
[[Category: Chymotrypsin]]
[[Category: Stichodactyla helianthus]]
[[Category: Betzel, C]]
[[Category: Betzel C]]
[[Category: Chavez, M A]]
[[Category: Chavez MA]]
[[Category: Dominguez, R]]
[[Category: Dominguez R]]
[[Category: Garcia-Fernandez, R]]
[[Category: Garcia-Fernandez R]]
[[Category: Gonzalez-Gonzalez, Y]]
[[Category: Gonzalez-Gonzalez Y]]
[[Category: Oberthuer, D]]
[[Category: Oberthuer D]]
[[Category: Pons, T]]
[[Category: Pons T]]
[[Category: Redecke, L]]
[[Category: Redecke L]]
[[Category: Chymotrypsin-inhibitor complex]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Kunitz-type serine protease inhibitor]]
[[Category: Secreted]]
Retrieved from "https://proteopedia.org/3t62"