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[[Image:1nar.gif|left|200px]]


{{Structure
==CRYSTAL STRUCTURE OF NARBONIN REFINED AT 1.8 ANGSTROMS RESOLUTION==
|PDB= 1nar |SIZE=350|CAPTION= <scene name='initialview01'>1nar</scene>, resolution 1.8&Aring;
<StructureSection load='1nar' size='340' side='right'caption='[[1nar]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=
<table><tr><td colspan='2'>[[1nar]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vicia_narbonensis Vicia narbonensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NAR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NAR FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nar FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nar OCA], [https://pdbe.org/1nar PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nar RCSB], [https://www.ebi.ac.uk/pdbsum/1nar PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nar ProSAT]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nar FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nar OCA], [http://www.ebi.ac.uk/pdbsum/1nar PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1nar RCSB]</span>
[https://www.uniprot.org/uniprot/Q08884_VICNA Q08884_VICNA]
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''CRYSTAL STRUCTURE OF NARBONIN REFINED AT 1.8 ANGSTROMS RESOLUTION'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/na/1nar_consurf.spt"</scriptWhenChecked>
==Overview==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
The three-dimensional structure of narbonin, a seed protein from Vicia narbonensis L, has been determined at 1.8 A resolution. Phase information was obtained by multiple isomorphous replacement and optimized anomalous dispersion. The narbonin structure was initially traced with only 17% amino-acid sequence information and preliminarily refined to a crystallographic R-factor of 16.5%. It is now refined to 15.9% using full sequence information derived from cDNA and after the addition of more solvent molecules. The monomeric molecule of narbonin is an eight-stranded parallel beta-barrel surrounded by alpha-helices in a beta/alpha-topology similar to that first observed in triose phosphate isomerase. Differences exist in the N-terminal part of the polypeptide chain, where the first helix is replaced by a loop and the second beta-strand is followed by an additional antiparallel alpha-sheet placed parallel on top of alpha-helices alpha3 and alpha4. Two short additional secondary structures are present. The first, an alpha-helix, is situated between the seventh beta-strand and the following helix, and the second, which is a 3(10) helix, between the eighth strand and the C-terminal helix. The most striking observation is the lack of a known enzymatic function for narbonin, because all TIM-like structures known so far are enzymes.
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nar ConSurf].
1NAR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Vicia_narbonensis Vicia narbonensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NAR OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
Crystal structure of narbonin at 1.8 A resolution., Hennig M, Pfeffer-Hennig S, Dauter Z, Wilson KS, Schlesier B, Nong VH, Acta Crystallogr D Biol Crystallogr. 1995 Mar 1;51(Pt 2):177-89. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15299319 15299319]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Vicia narbonensis]]
[[Category: Vicia narbonensis]]
[[Category: Hennig, M.]]
[[Category: Hennig M]]
[[Category: Schlesier, B.]]
[[Category: Schlesier B]]
[[Category: Wilson, K S.]]
[[Category: Wilson KS]]
[[Category: plant seed protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:27:44 2008''
Retrieved from "https://proteopedia.org/1nar"