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==A'-FORM RNA DOUBLE HELIX IN THE SINGLE CRYSTAL STRUCTURE OF R(UGAGCUUCGGCUC)==
==A'-FORM RNA DOUBLE HELIX IN THE SINGLE CRYSTAL STRUCTURE OF R(UGAGCUUCGGCUC)==
<StructureSection load='413d' size='340' side='right' caption='[[413d]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='413d' size='340' side='right'caption='[[413d]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[413d]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=373d 373d]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=413D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=413D FirstGlance]. <br>
<table><tr><td colspan='2'>[[413d]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=373d 373d]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=413D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=413D FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=413d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=413d OCA], [http://pdbe.org/413d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=413d RCSB], [http://www.ebi.ac.uk/pdbsum/413d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=413d ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=413d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=413d OCA], [https://pdbe.org/413d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=413d RCSB], [https://www.ebi.ac.uk/pdbsum/413d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=413d ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Here we demonstrate the presence of the A'-RNA conformation using the single crystal structure of a tridecamer: r(UGAGCUUCGGCUC). The average A'-RNA conformation deduced from X-ray fiber diffraction data had only been available previously, but now the presence of the A'-RNA conformation has been found in a single crystal structure for the first time. Statistical analysis showed that the A'-RNA conformation is distinguishable from the A-RNA conformation in a plot of the major groove width against the base pair inclination angle. The major groove of the A'-RNA conformation is wide enough to accommodate a protein or peptide while that of the A-RNA conformation is too narrow to do so. The presence of the A'-RNA conformation is significant for protein-RNA interaction.
A'-form RNA double helix in the single crystal structure of r(UGAGCUUCGGCUC).,Tanaka Y, Fujii S, Hiroaki H, Sakata T, Tanaka T, Uesugi S, Tomita K, Kyogoku Y Nucleic Acids Res. 1999 Feb 15;27(4):949-55. PMID:9927725<ref>PMID:9927725</ref>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 413d" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Fujii, S]]
[[Category: Large Structures]]
[[Category: Hiroaki, H]]
[[Category: Fujii S]]
[[Category: Kyogoku, Y]]
[[Category: Hiroaki H]]
[[Category: Sakata, T]]
[[Category: Kyogoku Y]]
[[Category: Tanaka, T]]
[[Category: Sakata T]]
[[Category: Tanaka, Y]]
[[Category: Tanaka T]]
[[Category: Tomita, K I]]
[[Category: Tanaka Y]]
[[Category: Uesugi, S]]
[[Category: Tomita K-I]]
[[Category: A'-rna]]
[[Category: Uesugi S]]
[[Category: Double helix]]
[[Category: Rna]]
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