2vy8: Difference between revisions
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==The 627-domain from influenza A virus polymerase PB2 subunit with Glu- 627== | ==The 627-domain from influenza A virus polymerase PB2 subunit with Glu- 627== | ||
<StructureSection load='2vy8' size='340' side='right' caption='[[2vy8]], [[Resolution|resolution]] 1.20Å' scene=''> | <StructureSection load='2vy8' size='340' side='right'caption='[[2vy8]], [[Resolution|resolution]] 1.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2vy8]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2vy8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus Influenza A virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VY8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VY8 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vy8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vy8 OCA], [https://pdbe.org/2vy8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vy8 RCSB], [https://www.ebi.ac.uk/pdbsum/2vy8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vy8 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PB2_I75A3 PB2_I75A3] Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication (By similarity). | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 18: | Line 20: | ||
==See Also== | ==See Also== | ||
*[[RNA polymerase|RNA polymerase]] | *[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Influenza A virus]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Crepin T]] | ||
[[Category: | [[Category: Cusack S]] | ||
[[Category: | [[Category: Guilligay D]] | ||
[[Category: | [[Category: Hart D]] | ||
[[Category: | [[Category: Ruigrok R]] | ||
[[Category: | [[Category: Tarendeau F]] | ||
