4p2j: Difference between revisions

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==Crystal structure of the mouse SNX19 PX domain with bound sulphate ion==
==Crystal structure of the mouse SNX19 PX domain with bound sulphate ion==
<StructureSection load='4p2j' size='340' side='right' caption='[[4p2j]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='4p2j' size='340' side='right'caption='[[4p2j]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4p2j]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P2J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P2J FirstGlance]. <br>
<table><tr><td colspan='2'>[[4p2j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P2J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4P2J FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p2j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p2j OCA], [http://pdbe.org/4p2j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p2j RCSB], [http://www.ebi.ac.uk/pdbsum/4p2j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4p2j ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4p2j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p2j OCA], [https://pdbe.org/4p2j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4p2j RCSB], [https://www.ebi.ac.uk/pdbsum/4p2j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4p2j ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SNX19_MOUSE SNX19_MOUSE] Plays a role in intracellular vesicle trafficking and exocytosis (PubMed:24843546). May play a role in maintaining insulin-containing dense core vesicles in pancreatic beta-cells and in preventing their degradation. May play a role in insulin secretion (PubMed:24843546). Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) (PubMed:25148684).<ref>PMID:24843546</ref> <ref>PMID:25148684</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Collins, B M]]
[[Category: Large Structures]]
[[Category: Phox homology domain]]
[[Category: Mus musculus]]
[[Category: Signaling protein]]
[[Category: Collins BM]]
[[Category: Sorting nexin]]
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