3t7l: Difference between revisions

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==Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution==
==Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution==
<StructureSection load='3t7l' size='340' side='right' caption='[[3t7l]], [[Resolution|resolution]] 1.09&Aring;' scene=''>
<StructureSection load='3t7l' size='340' side='right'caption='[[3t7l]], [[Resolution|resolution]] 1.09&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3t7l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T7L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T7L FirstGlance]. <br>
<table><tr><td colspan='2'>[[3t7l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T7L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T7L FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.09&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KIAA0305, ZFYVE16 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t7l OCA], [http://pdbe.org/3t7l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3t7l RCSB], [http://www.ebi.ac.uk/pdbsum/3t7l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3t7l ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t7l OCA], [https://pdbe.org/3t7l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t7l RCSB], [https://www.ebi.ac.uk/pdbsum/3t7l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t7l ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ZFY16_HUMAN ZFY16_HUMAN]] May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.<ref>PMID:11546807</ref> <ref>PMID:14613930</ref>
[https://www.uniprot.org/uniprot/ZFY16_HUMAN ZFY16_HUMAN] May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.<ref>PMID:11546807</ref> <ref>PMID:14613930</ref>  
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H]]
[[Category: Large Structures]]
[[Category: Berridge, G]]
[[Category: Arrowsmith CH]]
[[Category: Bountra, C]]
[[Category: Berridge G]]
[[Category: Bullock, A]]
[[Category: Bountra C]]
[[Category: Canning, P]]
[[Category: Bullock A]]
[[Category: Chaikuad, A]]
[[Category: Canning P]]
[[Category: Delft, F von]]
[[Category: Chaikuad A]]
[[Category: Edwards, A M]]
[[Category: Edwards AM]]
[[Category: Guo, K]]
[[Category: Guo K]]
[[Category: Krojer, T]]
[[Category: Krojer T]]
[[Category: Muniz, J R.C]]
[[Category: Muniz JRC]]
[[Category: Phillips, C]]
[[Category: Phillips C]]
[[Category: Structural genomic]]
[[Category: Sanvitale C]]
[[Category: Sanvitale, C]]
[[Category: Shrestha A]]
[[Category: Shrestha, A]]
[[Category: Weigelt J]]
[[Category: Weigelt, J]]
[[Category: Williams E]]
[[Category: Williams, E]]
[[Category: Von Delft F]]
[[Category: Lipid binding protein]]
[[Category: Sgc]]
[[Category: Transport protein]]
[[Category: Zinc finger]]
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