2yad: Difference between revisions
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==BRICHOS domain of Surfactant protein C precursor protein== | ==BRICHOS domain of Surfactant protein C precursor protein== | ||
<StructureSection load='2yad' size='340' side='right' caption='[[2yad]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='2yad' size='340' side='right'caption='[[2yad]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2yad]] is a 6 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2yad]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YAD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YAD FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yad FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yad OCA], [https://pdbe.org/2yad PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yad RCSB], [https://www.ebi.ac.uk/pdbsum/2yad PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yad ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Disease == | |||
[https://www.uniprot.org/uniprot/PSPC_HUMAN PSPC_HUMAN] Infant acute respiratory distress syndrome;Interstitial lung disease due to SP-C deficiency;Chronic respiratory distress with surfactant metabolism deficiency;Idiopathic pulmonary fibrosis. The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PSPC_HUMAN PSPC_HUMAN] Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Aqvist J]] | ||
[[Category: | [[Category: Arrowsmith CH]] | ||
[[Category: | [[Category: Askarieh G]] | ||
[[Category: Berglund | [[Category: Berglund H]] | ||
[[Category: Bergman | [[Category: Bergman T]] | ||
[[Category: Bountra | [[Category: Bountra C]] | ||
[[Category: Casals | [[Category: Casals C]] | ||
[[Category: Collins | [[Category: Collins R]] | ||
[[Category: Edwards | [[Category: Edwards AM]] | ||
[[Category: Ekblad | [[Category: Ekblad T]] | ||
[[Category: Flodin | [[Category: Flodin S]] | ||
[[Category: Flores | [[Category: Flores A]] | ||
[[Category: Graslund | [[Category: Graslund S]] | ||
[[Category: Hammarstrom | [[Category: Hammarstrom M]] | ||
[[Category: Hamvas | [[Category: Hamvas A]] | ||
[[Category: Hermansson | [[Category: Hermansson E]] | ||
[[Category: Johansson | [[Category: Johansson I]] | ||
[[Category: Johansson | [[Category: Johansson J]] | ||
[[Category: Jornvall | [[Category: Jornvall H]] | ||
[[Category: Karlberg | [[Category: Karlberg T]] | ||
[[Category: Keranen | [[Category: Keranen H]] | ||
[[Category: Knight | [[Category: Knight SD]] | ||
[[Category: Kol | [[Category: Kol S]] | ||
[[Category: Kotenyova | [[Category: Kotenyova T]] | ||
[[Category: Kouznetsova | [[Category: Kouznetsova E]] | ||
[[Category: Landreh | [[Category: Landreh M]] | ||
[[Category: Moche | [[Category: Moche M]] | ||
[[Category: Nogee | [[Category: Nogee LM]] | ||
[[Category: Nordling | [[Category: Nordling K]] | ||
[[Category: Nordlund | [[Category: Nordlund P]] | ||
[[Category: Nyman | [[Category: Nyman T]] | ||
[[Category: Persson | [[Category: Persson C]] | ||
[[Category: Presto | [[Category: Presto J]] | ||
[[Category: Saenz | [[Category: Saenz A]] | ||
[[Category: Schuler | [[Category: Schuler H]] | ||
[[Category: Siponen | [[Category: Siponen MI]] | ||
[[Category: Thorsell | [[Category: Thorsell AG]] | ||
[[Category: Tresaugues | [[Category: Tresaugues L]] | ||
[[Category: Wahlberg | [[Category: Wahlberg E]] | ||
[[Category: Weigelt | [[Category: Weigelt J]] | ||
[[Category: Welin | [[Category: Welin M]] | ||
[[Category: Westermark | [[Category: Westermark P]] | ||
[[Category: Willander | [[Category: Willander H]] | ||
[[Category: | [[Category: Van den Berg S]] | ||
