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==Crystal structure of a glycosylated beta-1,3-glucanase (HEV B 2), an allergen from Hevea brasiliensis==
==Crystal structure of a glycosylated beta-1,3-glucanase (HEV B 2), an allergen from Hevea brasiliensis==
<StructureSection load='4hpg' size='340' side='right' caption='[[4hpg]], [[Resolution|resolution]] 2.54&Aring;' scene=''>
<StructureSection load='4hpg' size='340' side='right'caption='[[4hpg]], [[Resolution|resolution]] 2.54&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4hpg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hevea_brasiliensis Hevea brasiliensis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3em5 3em5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HPG FirstGlance]. <br>
<table><tr><td colspan='2'>[[4hpg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hevea_brasiliensis Hevea brasiliensis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3em5 3em5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HPG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5364&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucan_endo-1,3-beta-D-glucosidase Glucan endo-1,3-beta-D-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.39 3.2.1.39] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hpg OCA], [https://pdbe.org/4hpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hpg RCSB], [https://www.ebi.ac.uk/pdbsum/4hpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hpg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hpg OCA], [http://pdbe.org/4hpg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hpg RCSB], [http://www.ebi.ac.uk/pdbsum/4hpg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hpg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A2TM14_HEVBR A2TM14_HEVBR]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Glucanase|Glucanase]]
*[[Glucanase 3D structures|Glucanase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Glucan endo-1,3-beta-D-glucosidase]]
[[Category: Hevea brasiliensis]]
[[Category: Hevea brasiliensis]]
[[Category: Hernandez-Santoyo, A]]
[[Category: Large Structures]]
[[Category: Rodriguez-Romero, A]]
[[Category: Hernandez-Santoyo A]]
[[Category: Allergen]]
[[Category: Rodriguez-Romero A]]
[[Category: Carbohydrate/sugar binding]]
[[Category: Gh17 family]]
[[Category: Glycoprotein]]
[[Category: Glycosidase hydrolase]]
[[Category: Glycoside hydrolase]]
[[Category: Glycosylation]]
[[Category: Hydrolase]]
[[Category: Latex]]
[[Category: Pathogenesis-related class-2 protein]]
[[Category: Tim barrel]]
Retrieved from "https://proteopedia.org/4hpg"