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==Structure of a Riboswitch-like RNA-ligand complex from the Hepatitis C Virus Internal Ribosome Entry Site==
==Structure of a Riboswitch-like RNA-ligand complex from the Hepatitis C Virus Internal Ribosome Entry Site==
<StructureSection load='3tzr' size='340' side='right' caption='[[3tzr]], [[Resolution|resolution]] 2.21&Aring;' scene=''>
<StructureSection load='3tzr' size='340' side='right'caption='[[3tzr]], [[Resolution|resolution]] 2.21&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3tzr]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TZR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TZR FirstGlance]. <br>
<table><tr><td colspan='2'>[[3tzr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TZR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TZR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SS0:(8R)-8-[(DIMETHYLAMINO)METHYL]-1-[3-(DIMETHYLAMINO)PROPYL]-1,7,8,9-TETRAHYDROCHROMENO[5,6-D]IMIDAZOL-2-AMINE'>SS0</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.212&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2nok|2nok]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SS0:(8R)-8-[(DIMETHYLAMINO)METHYL]-1-[3-(DIMETHYLAMINO)PROPYL]-1,7,8,9-TETRAHYDROCHROMENO[5,6-D]IMIDAZOL-2-AMINE'>SS0</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tzr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tzr OCA], [http://pdbe.org/3tzr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3tzr RCSB], [http://www.ebi.ac.uk/pdbsum/3tzr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3tzr ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tzr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tzr OCA], [https://pdbe.org/3tzr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tzr RCSB], [https://www.ebi.ac.uk/pdbsum/3tzr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tzr ProSAT]</span></td></tr>
</table>
</table>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bergdahl, B M]]
[[Category: Hepacivirus C]]
[[Category: Brunn, N]]
[[Category: Large Structures]]
[[Category: Dibrov, S M]]
[[Category: Bergdahl BM]]
[[Category: Ding, K]]
[[Category: Brunn N]]
[[Category: Hermann, T]]
[[Category: Dibrov SM]]
[[Category: Parker, M A]]
[[Category: Ding K]]
[[Category: Wyles, D L]]
[[Category: Hermann T]]
[[Category: Aminobenzimidazole binding]]
[[Category: Parker MA]]
[[Category: Internal loop]]
[[Category: Wyles DL]]
[[Category: Regulatory motif]]
[[Category: Rna]]

Latest revision as of 13:44, 14 March 2024

Structure of a Riboswitch-like RNA-ligand complex from the Hepatitis C Virus Internal Ribosome Entry Site

3tzr, resolution 2.21Å

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