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==Crystal Structure of BBBB at pH 10.0 with MPD as the cryoprotectant==
==Crystal Structure of BBBB at pH 10.0 with MPD as the cryoprotectant==
<StructureSection load='4kxo' size='340' side='right' caption='[[4kxo]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='4kxo' size='340' side='right'caption='[[4kxo]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4kxo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KXO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KXO FirstGlance]. <br>
<table><tr><td colspan='2'>[[4kxo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KXO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KXO FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ABO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fucosylgalactoside_3-alpha-galactosyltransferase Fucosylgalactoside 3-alpha-galactosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.37 2.4.1.37] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kxo OCA], [https://pdbe.org/4kxo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kxo RCSB], [https://www.ebi.ac.uk/pdbsum/4kxo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kxo ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kxo OCA], [http://pdbe.org/4kxo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kxo RCSB], [http://www.ebi.ac.uk/pdbsum/4kxo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kxo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4kxo" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4kxo" style="background-color:#fffaf0;"></div>
==See Also==
*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Fucosylgalactoside 3-alpha-galactosyltransferase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Alfaro, J A]]
[[Category: Alfaro JA]]
[[Category: Blackler, R J]]
[[Category: Blackler RJ]]
[[Category: Borisova, S N]]
[[Category: Borisova SN]]
[[Category: Evans, S V]]
[[Category: Evans SV]]
[[Category: Johal, A R]]
[[Category: Johal AR]]
[[Category: Schuman, B]]
[[Category: Schuman B]]
[[Category: Abo rossmann fold]]
[[Category: Blood group antigen]]
[[Category: Glycoprotein]]
[[Category: Manganese]]
[[Category: Metal-binding]]
[[Category: Retaining glycosyltransferase]]
[[Category: Transferase]]