4c49: Difference between revisions
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==Reactive loop cleaved human CBG in complex with cortisol== | ==Reactive loop cleaved human CBG in complex with cortisol== | ||
<StructureSection load='4c49' size='340' side='right' caption='[[4c49]], [[Resolution|resolution]] 2.70Å' scene=''> | <StructureSection load='4c49' size='340' side='right'caption='[[4c49]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4c49]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C49 OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[4c49]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C49 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C49 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HCY:(11ALPHA,14BETA)-11,17,21-TRIHYDROXYPREGN-4-ENE-3,20-DIONE'>HCY</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c49 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c49 OCA], [https://pdbe.org/4c49 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c49 RCSB], [https://www.ebi.ac.uk/pdbsum/4c49 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c49 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
[ | [https://www.uniprot.org/uniprot/CBG_HUMAN CBG_HUMAN] Corticosteroid-binding globulin deficiency. The disease is caused by mutations affecting the gene represented in this entry. | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/CBG_HUMAN CBG_HUMAN] Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.<ref>PMID:18513745</ref> | ||
==See Also== | |||
*[[Corticosteroid-binding globulin|Corticosteroid-binding globulin]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Chan WL]] | ||
[[Category: | [[Category: Read RJ]] | ||
[[Category: | [[Category: Zhou A]] | ||
Latest revision as of 12:03, 20 December 2023
Reactive loop cleaved human CBG in complex with cortisol
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