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==CRYSTAL STRUCTURE OF PTERIDINE REDUCTASE (PTR1) FROM LEISHMANIA DONOVANI==
==Crystal structure of pteridine reductase (PTR1) from Leishmania donovani==
<StructureSection load='2xox' size='340' side='right' caption='[[2xox]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2xox' size='340' side='right'caption='[[2xox]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xox]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Leido Leido]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XOX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XOX FirstGlance]. <br>
<table><tr><td colspan='2'>[[2xox]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_donovani Leishmania donovani]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XOX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XOX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pteridine_reductase Pteridine reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.33 1.5.1.33] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xox OCA], [http://pdbe.org/2xox PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xox RCSB], [http://www.ebi.ac.uk/pdbsum/2xox PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xox ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xox OCA], [https://pdbe.org/2xox PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xox RCSB], [https://www.ebi.ac.uk/pdbsum/2xox PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xox ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q6QDB5_LEIDO Q6QDB5_LEIDO]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Leido]]
[[Category: Large Structures]]
[[Category: Pteridine reductase]]
[[Category: Leishmania donovani]]
[[Category: Barrack, K L]]
[[Category: Barrack KL]]
[[Category: Burke, L A]]
[[Category: Burke LA]]
[[Category: Fyfe, P K]]
[[Category: Fyfe PK]]
[[Category: Hunter, W N]]
[[Category: Hunter WN]]
[[Category: Tulloch, L B]]
[[Category: Tulloch LB]]
[[Category: Antifolate]]
[[Category: Oxidoreductase]]
[[Category: Short-chain reductase]]

Latest revision as of 10:36, 20 December 2023

Crystal structure of pteridine reductase (PTR1) from Leishmania donovani

2xox, resolution 2.50Å

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