4gbf: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
 
(One intermediate revision by the same user not shown)
Line 1: Line 1:


==Crystal structure of the C-terminal domain of gp131 from bacteriophage phiKZ==
==Crystal structure of the C-terminal domain of gp131 from bacteriophage phiKZ==
<StructureSection load='4gbf' size='340' side='right' caption='[[4gbf]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='4gbf' size='340' side='right'caption='[[4gbf]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4gbf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpdpk Bpdpk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GBF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GBF FirstGlance]. <br>
<table><tr><td colspan='2'>[[4gbf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_virus_phiKZ Pseudomonas virus phiKZ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GBF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GBF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.949&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ORF131 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=169683 BPDPK])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gbf OCA], [http://pdbe.org/4gbf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gbf RCSB], [http://www.ebi.ac.uk/pdbsum/4gbf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gbf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gbf OCA], [https://pdbe.org/4gbf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gbf RCSB], [https://www.ebi.ac.uk/pdbsum/4gbf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gbf ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
== Function ==
== Publication Abstract from PubMed ==
[https://www.uniprot.org/uniprot/Q8SD31_BPDPK Q8SD31_BPDPK]
Pseudomonas phage varphiKZ and its two close relatives varphiPA3 and 201varphi2-1 are very large bacteriophages that form a separate branch in phage classification because their genomes are very different from the rest of GenBank sequence data. The contractile tail of varphiKZ is built from at least 32 different proteins, but a definitive structural function is assigned to only one of them-the tail sheath protein. Here, we report the crystal structure of the C-terminal domain of another phiKZ tail protein, gene product 131 (gp131C). We show that gp131 is located at the periphery of the baseplate and possibly associates with fibers that emanate from the baseplate. Gp131C is a seven-bladed beta-propeller that has a shape of a skewed toroid. A small but highly conserved and negatively charged patch on the surface of gp131C might be important for substrate binding or for interaction with a different tail protein.
 
Crystal structure and location of gp131 in the bacteriophage phiKZ virion.,Sycheva LV, Shneider MM, Sykilinda NN, Ivanova MA, Miroshnikov KA, Leiman PG Virology. 2012 Sep 29. pii: S0042-6822(12)00442-4. doi:, 10.1016/j.virol.2012.09.001. PMID:23031178<ref>PMID:23031178</ref>
 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 4gbf" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bpdpk]]
[[Category: Large Structures]]
[[Category: Leiman, P G]]
[[Category: Pseudomonas virus phiKZ]]
[[Category: Shneider, M M]]
[[Category: Leiman PG]]
[[Category: Sycheva, L V]]
[[Category: Shneider MM]]
[[Category: 7-bladed beta-propeller]]
[[Category: Sycheva LV]]
[[Category: At the periphery of the baseplate or in the fiber of bacteriophage phikz]]
[[Category: Possibly participates in binding of the phage to the host cell]]
[[Category: Viral protein]]
Retrieved from "https://proteopedia.org/4gbf"