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==Crystal structure of yeast glycogen synthase E169Q mutant in complex with glucose and UDP==
==Crystal structure of yeast glycogen synthase E169Q mutant in complex with glucose and UDP==
<StructureSection load='4kqm' size='340' side='right' caption='[[4kqm]], [[Resolution|resolution]] 2.77&Aring;' scene=''>
<StructureSection load='4kqm' size='340' side='right'caption='[[4kqm]], [[Resolution|resolution]] 2.77&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4kqm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KQM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KQM FirstGlance]. <br>
<table><tr><td colspan='2'>[[4kqm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_FostersO Saccharomyces cerevisiae FostersO]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KQM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KQM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=G6P:ALPHA-D-GLUCOSE-6-PHOSPHATE'>G6P</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.77&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4kq1|4kq1]], [[4kq2|4kq2]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=G6P:ALPHA-D-GLUCOSE-6-PHOSPHATE'>G6P</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FOSTERSO_3265, GSY2 YLR258W L8479.8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=764101 Baker's yeast])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kqm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kqm OCA], [https://pdbe.org/4kqm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kqm RCSB], [https://www.ebi.ac.uk/pdbsum/4kqm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kqm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kqm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kqm OCA], [http://pdbe.org/4kqm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kqm RCSB], [http://www.ebi.ac.uk/pdbsum/4kqm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kqm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GYS2_YEAST GYS2_YEAST] Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. Is believed to regulate the synthesis of glycogen.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Baker's yeast]]
[[Category: Large Structures]]
[[Category: Chikwana, V M]]
[[Category: Saccharomyces cerevisiae FostersO]]
[[Category: Hurley, T D]]
[[Category: Chikwana VM]]
[[Category: Glucosyltransferase]]
[[Category: Hurley TD]]
[[Category: Gt-b]]
[[Category: Rossmann fold]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/4kqm"