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[[Image:1odd.jpg|left|200px]]


{{Structure
==OMPR C-TERMINAL DOMAIN (OMPR-C) FROM ESCHERICHIA COLI==
|PDB= 1odd |SIZE=350|CAPTION= <scene name='initialview01'>1odd</scene>, resolution 2.2&Aring;
<StructureSection load='1odd' size='340' side='right'caption='[[1odd]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
|SITE=
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1odd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ODD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ODD FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1odd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1odd OCA], [https://pdbe.org/1odd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1odd RCSB], [https://www.ebi.ac.uk/pdbsum/1odd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1odd ProSAT]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1odd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1odd OCA], [http://www.ebi.ac.uk/pdbsum/1odd PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1odd RCSB]</span>
[https://www.uniprot.org/uniprot/OMPR_ECOLI OMPR_ECOLI] The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the OmpR protein. As a multimer, it turns on the expression of the ompC gene; as a monomer, it turns on the expression of the ompF gene.
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''OMPR C-TERMINAL DOMAIN (OMPR-C) FROM ESCHERICHIA COLI'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/od/1odd_consurf.spt"</scriptWhenChecked>
==Overview==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
The C-terminal DNA-binding domain of OmpR, a positive regulator involved in osmoregulation expression of the ompF and ompC genes in Escherichia coli, has a helix-turn-helix variant motif. The 'turn' region, consisting of 11 residues, forms an RNA polymerase contact site.
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1odd ConSurf].
1ODD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ODD OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
Escherichia coli positive regulator OmpR has a large loop structure at the putative RNA polymerase interaction site., Kondo H, Nakagawa A, Nishihira J, Nishimura Y, Mizuno T, Tanaka I, Nat Struct Biol. 1997 Jan;4(1):28-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8989318 8989318]
[[Category: Escherichia coli K-12]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Kondou H]]
[[Category: Kondou, H.]]
[[Category: Nakagawa A]]
[[Category: Nakagawa, A.]]
[[Category: Tanaka I]]
[[Category: Tanaka, I.]]
[[Category: dna binding domain]]
[[Category: gene regulatory protein]]
[[Category: positive response regulator]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:43:35 2008''

Latest revision as of 08:01, 14 February 2024

OMPR C-TERMINAL DOMAIN (OMPR-C) FROM ESCHERICHIA COLI

1odd, resolution 2.20Å

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