5lr7: Difference between revisions

(2 intermediate revisions by the same user not shown)

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5lr7 is ~~ON HOLD until Paper Publication~~

==CRYSTAL STRUCTURE OF HSP90 IN COMPLEX WITH SAR567530==

== Structural highlights ==

<table><tr><td colspan='2'>[[5lr7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LR7 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=5LR7 FirstGlance].

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=73J:~{N}-[(9~{R})-4-(5-fluoranyl-1~{H}-benzimidazol-2-yl)-9~{H}-fluoren-9-yl]-1~{H}-pyrrolo[2,3-b]pyridine-4-carboxamide'>73J</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=5lr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lr7 OCA], [https://pdbe.org/5lr7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lr7 RCSB], [https://www.ebi.ac.uk/pdbsum/5lr7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lr7 ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>

~~Authors: VALLEE, F., DUPUY, A.~~

==See Also==

*[[Heat Shock Protein structures|Heat Shock Protein structures]]

~~Description~~: ~~CRYSTAL STRUCTURE OF HSP90 IN COMPLEX WITH SAR567530~~

== References ==

[[Category: ~~Unreleased~~ Structures]]

[[Category: Dupuy, A]]

__TOC__

[[Category: Vallee, F]]

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Dupuy A]]

[[Category: Vallee F]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5lr7 is ON HOLD  until Paper Publication
+==CRYSTAL STRUCTURE OF HSP90 IN COMPLEX WITH SAR567530==
+<StructureSection load='5lr7' size='340' side='right'caption='[[5lr7]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5lr7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LR7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LR7 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=73J:~{N}-[(9~{R})-4-(5-fluoranyl-1~{H}-benzimidazol-2-yl)-9~{H}-fluoren-9-yl]-1~{H}-pyrrolo[2,3-b]pyridine-4-carboxamide'>73J</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lr7 OCA], [https://pdbe.org/5lr7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lr7 RCSB], [https://www.ebi.ac.uk/pdbsum/5lr7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lr7 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>
-Authors: VALLEE, F., DUPUY, A.
+==See Also==
+*[[Heat Shock Protein structures|Heat Shock Protein structures]]
-Description: CRYSTAL STRUCTURE OF HSP90 IN COMPLEX WITH SAR567530
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
-[[Category: Dupuy, A]]
+__TOC__
-[[Category: Vallee, F]]
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Dupuy A]]
+[[Category: Vallee F]]