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[[Image:1omi.gif|left|200px]]


{{Structure
==Crystal structure of PrfA,the transcriptional regulator in Listeria monocytogenes==
|PDB= 1omi |SIZE=350|CAPTION= <scene name='initialview01'>1omi</scene>, resolution 2.8&Aring;
<StructureSection load='1omi' size='340' side='right'caption='[[1omi]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
<table><tr><td colspan='2'>[[1omi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OMI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OMI FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
|GENE= PRFA OR LMO0200 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1639 Listeria monocytogenes])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00027 cNMP_binding], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG0664 Crp]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1omi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1omi OCA], [https://pdbe.org/1omi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1omi RCSB], [https://www.ebi.ac.uk/pdbsum/1omi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1omi ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1omi TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1omi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1omi OCA], [http://www.ebi.ac.uk/pdbsum/1omi PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1omi RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/PRFA_LISMO PRFA_LISMO] Positively regulates expression of listeriolysin, of 1-phosphadidylinositol phosphodiesterase (PI-PLC) and other virulence factors.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/om/1omi_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1omi ConSurf].
<div style="clear:both"></div>


'''Crystal structure of PrfA,the transcriptional regulator in Listeria monocytogenes'''
==See Also==
 
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1OMI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OMI OCA].
[[Category: Large Structures]]
[[Category: Listeria monocytogenes]]
[[Category: Listeria monocytogenes]]
[[Category: Single protein]]
[[Category: Almo SC]]
[[Category: Almo, S C.]]
[[Category: Burley SK]]
[[Category: Burley, S K.]]
[[Category: Chance MR]]
[[Category: Chance, M R.]]
[[Category: Cossart P]]
[[Category: Cossart, P.]]
[[Category: Dodatko T]]
[[Category: Dodatko, T.]]
[[Category: Fedorov AA]]
[[Category: Fedorov, A A.]]
[[Category: Rajashankar K]]
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
[[Category: Thirumuruhan R]]
[[Category: Rajashankar, K.]]
[[Category: Thirumuruhan, R.]]
[[Category: cap fold]]
[[Category: listeria monocytogene]]
[[Category: new york structural genomix research consortium]]
[[Category: nysgxrc]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
[[Category: transcriptional regulator prfa]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:47:22 2008''
Retrieved from "https://proteopedia.org/1omi"