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==The structure of the S37P MS2 viral capsid assembly.==
==The structure of the S37P MS2 viral capsid assembly.==
<StructureSection load='4zor' size='340' side='right' caption='[[4zor]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4zor' size='340' side='right'caption='[[4zor]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4zor]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZOR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZOR FirstGlance]. <br>
<table><tr><td colspan='2'>[[4zor]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_MS2 Escherichia virus MS2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZOR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZOR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zor OCA], [http://pdbe.org/4zor PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zor RCSB], [http://www.ebi.ac.uk/pdbsum/4zor PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zor ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zor OCA], [https://pdbe.org/4zor PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zor RCSB], [https://www.ebi.ac.uk/pdbsum/4zor PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zor ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.  
[https://www.uniprot.org/uniprot/CAPSD_BPMS2 CAPSD_BPMS2] Self-assembles to form the T=3 icosahedral virus shell that protects the viral nucleic acid. Acts as a translational repressor by binding with high specificity to a single stem-loop structure in the genomic RNA that contains the initiation codon of the gene for the viral replicase. Involved in virus assembly through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome.<ref>PMID:16531233</ref> <ref>PMID:18662904</ref> <ref>PMID:26608810</ref> <ref>PMID:8254664</ref> <ref>PMID:9245600</ref> <ref>PMID:9469847</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Asensio, M A]]
[[Category: Escherichia virus MS2]]
[[Category: Sankaran, B]]
[[Category: Large Structures]]
[[Category: Tullman-Ercek, D]]
[[Category: Asensio MA]]
[[Category: Zwart, P H]]
[[Category: Sankaran B]]
[[Category: Capsid]]
[[Category: Tullman-Ercek D]]
[[Category: Virus]]
[[Category: Zwart PH]]
[[Category: Virus like particle]]