5ltl: Difference between revisions

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New page: '''Unreleased structure''' The entry 5ltl is ON HOLD Authors: Weiergraeber, O.H., Batra-Safferling, R., Haenel, K., Willbold, D. Description: Structure of human chemokine CCL16 [[Categ...
 
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'''Unreleased structure'''


The entry 5ltl is ON HOLD
==Structure of human chemokine CCL16==
 
<StructureSection load='5ltl' size='340' side='right'caption='[[5ltl]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
Authors: Weiergraeber, O.H., Batra-Safferling, R., Haenel, K., Willbold, D.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5ltl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LTL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LTL FirstGlance]. <br>
Description: Structure of human chemokine CCL16
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
[[Category: Willbold, D]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ltl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ltl OCA], [https://pdbe.org/5ltl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ltl RCSB], [https://www.ebi.ac.uk/pdbsum/5ltl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ltl ProSAT]</span></td></tr>
[[Category: Batra-Safferling, R]]
</table>
[[Category: Haenel, K]]
== Function ==
[[Category: Weiergraeber, O.H]]
[https://www.uniprot.org/uniprot/CCL16_HUMAN CCL16_HUMAN] Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Batra-Safferling R]]
[[Category: Haenel K]]
[[Category: Weiergraeber OH]]
[[Category: Willbold D]]
Retrieved from "https://proteopedia.org/5ltl"