5lug: Difference between revisions

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'''Unreleased structure'''


The entry 5lug is ON HOLD
==Crystal structure of human Spindlin-2B protein in complex with ART(M3L)QTA(2MR)KS peptide==
<StructureSection load='5lug' size='340' side='right'caption='[[5lug]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5lug]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LUG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LUG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lug OCA], [https://pdbe.org/5lug PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lug RCSB], [https://www.ebi.ac.uk/pdbsum/5lug PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lug ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SPI2B_HUMAN SPI2B_HUMAN] Involved in the regulation of cell cycle progression, this activity is related to the inhibition of apoptosis following the removal of essential growth factors (PubMed:12145692). Exhibits H3K4me3-binding activity (PubMed:29061846).<ref>PMID:12145692</ref> <ref>PMID:29061846</ref>


Authors: Srikannathasan, V., Gileadi, C., Talon, R., Shrestha, L, Kopec, J, Szykowska, A., Burgess-Brown, N., Arrowsmith, C.H., Edwards, A.M., Bountra, C., von Delft, F., Oppermann, U., Huber, K.
==See Also==
 
*[[Spindlin|Spindlin]]
Description: Crystal structure of human Spindlin-2B protein in complex with ART(M3L)QTA(2MR)KS peptide
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Burgess-Brown, N]]
__TOC__
[[Category: Shrestha, L, Kopec, J, Szykowska, A]]
</StructureSection>
[[Category: Bountra, C]]
[[Category: Homo sapiens]]
[[Category: Huber, K]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C.H]]
[[Category: Arrowsmith CH]]
[[Category: Gileadi, C]]
[[Category: Bountra C]]
[[Category: Oppermann, U]]
[[Category: Burgess-Brown N]]
[[Category: Von Delft, F]]
[[Category: Edwards AM]]
[[Category: Edwards, A.M]]
[[Category: Gileadi C]]
[[Category: Talon, R]]
[[Category: Huber K]]
[[Category: Srikannathasan, V]]
[[Category: Kopec J]]
[[Category: Oppermann U]]
[[Category: Shrestha L]]
[[Category: Srikannathasan V]]
[[Category: Szykowska A]]
[[Category: Talon R]]
[[Category: Von Delft F]]

Latest revision as of 18:50, 18 October 2023

Crystal structure of human Spindlin-2B protein in complex with ART(M3L)QTA(2MR)KS peptide

5lug, resolution 1.70Å

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