TolR: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| (6 intermediate revisions by 2 users not shown) | |||
| Line 1: | Line 1: | ||
<StructureSection load='' size='350' side='right' scene='TolR/Tolrstructure/1' caption='TolR periplasmic domain dimer (PDB code [[2jwk]])'> | |||
==Structure== | ==Structure== | ||
'''TolR''' is a bitopic protein located in the inner membrane and consists of three domains: domain I (from residues 1 to 43 and including the transmembrane domain between residues 23 to 43), domain II and domain III from residues 117 to 142<ref name='Journet'>PMID: 10419942</ref>. Domains II and III have the ability to dimerize, but unlike domains I and III, domain II is poorly conserved<ref>PMID: 11994151</ref>. For additional details see [[Tol]]. | '''TolR''' is a bitopic protein (protein having a single α helix in its transmembrane domain) located in the inner membrane and consists of three domains: domain I (from residues 1 to 43 and including the transmembrane domain between residues 23 to 43), domain II and domain III from residues 117 to 142<ref name='Journet'>PMID: 10419942</ref>. Domains II and III have the ability to dimerize, but unlike domains I and III, domain II is poorly conserved<ref>PMID: 11994151</ref>. For additional details see [[Tol]]. | ||
Domain III has been suggested to form an amphiphilic α-helix, which play an essential role in the functional assembly of the [[Tol]] complex<ref name='Lazzaroni'>PMID: 7853390</ref>. | Domain III has been suggested to form an amphiphilic α-helix, which play an essential role in the functional assembly of the [[Tol]] complex<ref name='Lazzaroni'>PMID: 7853390</ref>. | ||
| Line 13: | Line 12: | ||
# [[Colicin A]] import | # [[Colicin A]] import | ||
# Maintaining cell envelope integrity | # Maintaining cell envelope integrity | ||
</StructureSection> | |||
==3D structures of TolR== | |||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | |||
[[2jwk]], [[2jwl]] – TolR periplasmic domain – ''Haemophilus influenzae'' – NMR<br /> | [[2jwk]], [[2jwl]] – TolR periplasmic domain – ''Haemophilus influenzae'' – NMR<br /> | ||
[[5by4]] – | [[5by4]] – EcTolR – ''Escherichia coli''<br /> | ||
[[8odt]] – EcTolR + TolQ – Cryo EM<br /> | |||
==References== | ==References== | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | |||
