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==T4 Lysozyme L99A/M102Q with Benzene Bound==
==T4 Lysozyme L99A/M102Q with Benzene Bound==
<StructureSection load='5jwt' size='340' side='right' caption='[[5jwt]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
<StructureSection load='5jwt' size='340' side='right'caption='[[5jwt]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5jwt]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JWT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JWT FirstGlance]. <br>
<table><tr><td colspan='2'>[[5jwt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JWT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JWT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BNZ:BENZENE'>BNZ</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.41&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jwu|5jwu]], [[5jwv|5jwv]], [[5jww|5jww]], [[5jwx|5jwx]], [[5jws|5jws]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BNZ:BENZENE'>BNZ</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jwt OCA], [https://pdbe.org/5jwt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jwt RCSB], [https://www.ebi.ac.uk/pdbsum/5jwt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jwt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jwt OCA], [http://pdbe.org/5jwt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jwt RCSB], [http://www.ebi.ac.uk/pdbsum/5jwt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jwt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4]] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5jwt" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5jwt" style="background-color:#fffaf0;"></div>
==See Also==
*[[Lysin 3D structures|Lysin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lysozyme]]
[[Category: Escherichia virus T4]]
[[Category: Fischer, M]]
[[Category: Large Structures]]
[[Category: Lee, H]]
[[Category: Fischer M]]
[[Category: Liu, S Y]]
[[Category: Lee H]]
[[Category: Shoichet, B K]]
[[Category: Liu S-Y]]
[[Category: Hydrolase]]
[[Category: Shoichet BK]]
[[Category: Phage lysozyme azaborine]]

Latest revision as of 09:49, 27 September 2023

T4 Lysozyme L99A/M102Q with Benzene Bound

5jwt, resolution 1.41Å

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