5tf6: Difference between revisions
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==Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core== | |||
<StructureSection load='5tf6' size='340' side='right'caption='[[5tf6]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5tf6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TF6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TF6 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tf6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tf6 OCA], [https://pdbe.org/5tf6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tf6 RCSB], [https://www.ebi.ac.uk/pdbsum/5tf6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tf6 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PRP24_YEAST PRP24_YEAST] Binds preferentially to the U4/U6 hybrid snRNAs. Can stimulate the annealing of U4 and U6. Could participate in both the formation and disassembly of the U4/U6 hybrid during splicing. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Saccharomyces cerevisiae S288C]] | |||
[[Category: Brow DA]] | |||
[[Category: Butcher SE]] | |||
[[Category: Montemayor EJ]] | |||
Latest revision as of 14:20, 6 March 2024
Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core
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