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==Flavodiiron core of Escherichia coli flavorubredoxin in the reduced form.==
==Flavodiiron core of Escherichia coli flavorubredoxin in the reduced form.==
<StructureSection load='5lld' size='340' side='right' caption='[[5lld]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
<StructureSection load='5lld' size='340' side='right'caption='[[5lld]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5lld]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LLD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LLD FirstGlance]. <br>
<table><tr><td colspan='2'>[[5lld]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LLD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LLD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.651&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4d02|4d02]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lld FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lld OCA], [http://pdbe.org/5lld PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lld RCSB], [http://www.ebi.ac.uk/pdbsum/5lld PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lld ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lld FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lld OCA], [https://pdbe.org/5lld PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lld RCSB], [https://www.ebi.ac.uk/pdbsum/5lld PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lld ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NORV_ECOLI NORV_ECOLI]] Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the reductase at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase.<ref>PMID:11751865</ref> <ref>PMID:12101220</ref>
[https://www.uniprot.org/uniprot/NORV_ECOLI NORV_ECOLI] Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the reductase at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase.<ref>PMID:11751865</ref> <ref>PMID:12101220</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Borges, P T]]
[[Category: Escherichia coli K-12]]
[[Category: Carrondo, M A]]
[[Category: Large Structures]]
[[Category: Frazao, C]]
[[Category: Borges PT]]
[[Category: Romao, C V]]
[[Category: Carrondo MA]]
[[Category: Teixeira, M]]
[[Category: Frazao C]]
[[Category: Vicente, J B]]
[[Category: Romao CV]]
[[Category: Diiron center]]
[[Category: Teixeira M]]
[[Category: Flavodiiron protein]]
[[Category: Vicente JB]]
[[Category: Flavorubredoxin]]
[[Category: Nitric oxide reductase]]
[[Category: Oxidoreductase]]