5mfx: Difference between revisions
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==Zika NS3 helicase:RNA complex== | |||
<StructureSection load='5mfx' size='340' side='right'caption='[[5mfx]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5mfx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Zika_virus Zika virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MFX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MFX FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.598Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mfx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mfx OCA], [https://pdbe.org/5mfx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mfx RCSB], [https://www.ebi.ac.uk/pdbsum/5mfx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mfx ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A146CJH9_ZIKV A0A146CJH9_ZIKV] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859] | |||
==See Also== | |||
*[[Virus protease 3D structures|Virus protease 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Antson | [[Category: Zika virus]] | ||
[[Category: Chechik | [[Category: Antson AA]] | ||
[[Category: Ge | [[Category: Chechik M]] | ||
[[Category: Jenkins | [[Category: Ge M]] | ||
[[Category: Greive SJ]] | |||
[[Category: Jenkins HT]] | |||
