5u0p: Difference between revisions
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New page: '''Unreleased structure''' The entry 5u0p is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Cryo-EM structure of the transcriptional Mediator== | |||
<SX load='5u0p' size='340' side='right' viewer='molstar' caption='[[5u0p]], [[Resolution|resolution]] 4.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5u0p]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U0P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5U0P FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.4Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5u0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u0p OCA], [https://pdbe.org/5u0p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5u0p RCSB], [https://www.ebi.ac.uk/pdbsum/5u0p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5u0p ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MED7_SCHPO MED7_SCHPO] Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | |||
==See Also== | |||
*[[Mediator|Mediator]] | |||
__TOC__ | |||
[[Category: | </SX> | ||
[[Category: Large Structures]] | |||
[[Category: Schizosaccharomyces pombe]] | |||
[[Category: Asturias F]] | |||
[[Category: Chao T-C]] | |||
[[Category: Conaway JW]] | |||
[[Category: Conaway RC]] | |||
[[Category: Florens L]] | |||
[[Category: Gopalan S]] | |||
[[Category: Murakami K]] | |||
[[Category: Tsai K-L]] | |||
[[Category: Washburn MP]] | |||
[[Category: Yu X]] | |||
[[Category: Zhang Y]] | |||
Latest revision as of 15:44, 6 March 2024
Cryo-EM structure of the transcriptional Mediator
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