5l0o: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(One intermediate revision by the same user not shown)
Line 1: Line 1:


==IQGAP1 calponin homology domain fragment (CHDF) mutant K161C under oxidizing conditions==
==IQGAP1 calponin homology domain fragment (CHDF) mutant K161C under oxidizing conditions==
<StructureSection load='5l0o' size='340' side='right' caption='[[5l0o]], [[Resolution|resolution]] 2.36&Aring;' scene=''>
<StructureSection load='5l0o' size='340' side='right'caption='[[5l0o]], [[Resolution|resolution]] 2.36&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5l0o]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L0O FirstGlance]. <br>
<table><tr><td colspan='2'>[[5l0o]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5L0O FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3i6x|3i6x]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.36&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l0o OCA], [http://pdbe.org/5l0o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l0o RCSB], [http://www.ebi.ac.uk/pdbsum/5l0o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l0o ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5l0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l0o OCA], [https://pdbe.org/5l0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5l0o RCSB], [https://www.ebi.ac.uk/pdbsum/5l0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5l0o ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/IQGA1_HUMAN IQGA1_HUMAN]] Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.<ref>PMID:15695813</ref>
[https://www.uniprot.org/uniprot/IQGA1_HUMAN IQGA1_HUMAN] Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.<ref>PMID:15695813</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 22:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Liu, J]]
[[Category: Homo sapiens]]
[[Category: Worthylake, D]]
[[Category: Large Structures]]
[[Category: Calponin homology]]
[[Category: Liu J]]
[[Category: Disulfide-bonded dimer]]
[[Category: Worthylake D]]
[[Category: Signaling protein]]