5gnu: Difference between revisions
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==the structure of mini-MFN1 apo== | ==the structure of mini-MFN1 apo== | ||
<StructureSection load='5gnu' size='340' side='right' caption='[[5gnu]], [[Resolution|resolution]] 4.11Å' scene=''> | <StructureSection load='5gnu' size='340' side='right'caption='[[5gnu]], [[Resolution|resolution]] 4.11Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5gnu]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GNU OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5gnu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GNU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GNU FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.113Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gnu OCA], [https://pdbe.org/5gnu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gnu RCSB], [https://www.ebi.ac.uk/pdbsum/5gnu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gnu ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/MFN1_HUMAN MFN1_HUMAN] Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.<ref>PMID:11181170</ref> <ref>PMID:12475957</ref> <ref>PMID:12759376</ref> <ref>PMID:23921378</ref> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Lou J]] | ||
[[Category: | [[Category: Lou Z]] | ||
[[Category: | [[Category: Ming Z]] | ||
[[Category: | [[Category: Rao Z]] | ||
[[Category: | [[Category: Yan L]] | ||
[[Category: | [[Category: Yu C]] | ||
