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==Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) Mutant S337C N664C to 2.06-A resolution==
==Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) Mutant S337C N664C to 2.06-A resolution==
<StructureSection load='3tey' size='340' side='right' caption='[[3tey]], [[Resolution|resolution]] 2.12&Aring;' scene=''>
<StructureSection load='3tey' size='340' side='right'caption='[[3tey]], [[Resolution|resolution]] 2.12&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3tey]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_cereus_var._anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TEY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TEY FirstGlance]. <br>
<table><tr><td colspan='2'>[[3tey]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TEY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TEY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.12&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tew|3tew]], [[3tex|3tex]], [[3tez|3tez]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BXA0164, GBAA_pXO1_0164, pag, pagA, PX01, pXO1-110 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 "Bacillus cereus var. anthracis" (Cohn 1872) Smith et al. 1946])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tey FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tey OCA], [https://pdbe.org/3tey PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tey RCSB], [https://www.ebi.ac.uk/pdbsum/3tey PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tey ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tey FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tey OCA], [http://pdbe.org/3tey PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3tey RCSB], [http://www.ebi.ac.uk/pdbsum/3tey PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3tey ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PAG_BACAN PAG_BACAN] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 3tey" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3tey" style="background-color:#fffaf0;"></div>
==See Also==
*[[Anthrax protective antigen|Anthrax protective antigen]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Feld, G K]]
[[Category: Bacillus anthracis]]
[[Category: Krantz, B A]]
[[Category: Large Structures]]
[[Category: Protein transport]]
[[Category: Feld GK]]
[[Category: Toxin]]
[[Category: Krantz BA]]
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