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==Crystal structure of the Fab fragment of anti-HER2 antibody 4D5 with redesigned heavy and light chain interfaces==
==Crystal structure of the Fab fragment of anti-HER2 antibody 4D5 with redesigned heavy and light chain interfaces==
<StructureSection load='5tdo' size='340' side='right' caption='[[5tdo]], [[Resolution|resolution]] 1.61&Aring;' scene=''>
<StructureSection load='5tdo' size='340' side='right'caption='[[5tdo]], [[Resolution|resolution]] 1.61&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5tdo]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TDO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TDO FirstGlance]. <br>
<table><tr><td colspan='2'>[[5tdo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TDO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TDO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.61&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fve|1fve]], [[5tdn|5tdn]], [[5tdp|5tdp]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tdo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tdo OCA], [http://pdbe.org/5tdo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tdo RCSB], [http://www.ebi.ac.uk/pdbsum/5tdo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tdo ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tdo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tdo OCA], [https://pdbe.org/5tdo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tdo RCSB], [https://www.ebi.ac.uk/pdbsum/5tdo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tdo ProSAT]</span></td></tr>
</table>
</table>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Carter, P J]]
[[Category: Homo sapiens]]
[[Category: Yin, Y]]
[[Category: Large Structures]]
[[Category: Antibody]]
[[Category: Carter PJ]]
[[Category: Fab]]
[[Category: Yin Y]]
[[Category: Immune system]]
[[Category: Immunoglobulin]]