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[[Image:1qwr.jpg|left|200px]]


{{Structure
==Crystal Structure Analysis of the Mannose 6-Phosphate Isomerase from Bacillus subtilis==
|PDB= 1qwr |SIZE=350|CAPTION= <scene name='initialview01'>1qwr</scene>, resolution 1.80&Aring;
<StructureSection load='1qwr' size='340' side='right'caption='[[1qwr]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
<table><tr><td colspan='2'>[[1qwr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QWR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QWR FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannose-6-phosphate_isomerase Mannose-6-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.8 5.3.1.8] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
|GENE= PMI OR BSU35790 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam01238 PMI_typeI], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1482 ManA]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qwr OCA], [https://pdbe.org/1qwr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qwr RCSB], [https://www.ebi.ac.uk/pdbsum/1qwr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qwr ProSAT], [https://www.topsan.org/Proteins/MCSG/1qwr TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qwr OCA], [http://www.ebi.ac.uk/pdbsum/1qwr PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1qwr RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/MANA3_BACSU MANA3_BACSU]
 
== Evolutionary Conservation ==
'''Crystal Structure Analysis of the Mannose 6-Phosphate Isomerase from Bacillus subtilis'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qw/1qwr_consurf.spt"</scriptWhenChecked>
1QWR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QWR OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qwr ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Mannose-6-phosphate isomerase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Joachimiak A]]
[[Category: Joachimiak, A.]]
[[Category: Kim Y]]
[[Category: Kim, Y.]]
[[Category: Lezondra L]]
[[Category: Lezondra, L.]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: d-mannose 6-phosphate]]
[[Category: isomerase]]
[[Category: mcsg]]
[[Category: midwest center for structural genomic]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:20:05 2008''

Latest revision as of 07:16, 30 October 2024

Crystal Structure Analysis of the Mannose 6-Phosphate Isomerase from Bacillus subtilis

1qwr, resolution 1.80Å

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