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[[Image:1r79.gif|left|200px]]


{{Structure
==Solution Structure of The C1 Domain of The Human Diacylglycerol Kinase Delta==
|PDB= 1r79 |SIZE=350|CAPTION= <scene name='initialview01'>1r79</scene>
<StructureSection load='1r79' size='340' side='right'caption='[[1r79]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
<table><tr><td colspan='2'>[[1r79]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R79 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R79 FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Diacylglycerol_kinase Diacylglycerol kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.107 2.7.1.107] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= KAZUSA cDNA ha00914 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r79 OCA], [https://pdbe.org/1r79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r79 RCSB], [https://www.ebi.ac.uk/pdbsum/1r79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r79 ProSAT], [https://www.topsan.org/Proteins/RSGI/1r79 TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1r79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r79 OCA], [http://www.ebi.ac.uk/pdbsum/1r79 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1r79 RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/DGKD_HUMAN DGKD_HUMAN] May function as signaling molecule.<ref>PMID:17880279</ref>  Isoform 2 may be involved in cell growth and tumorigenesis. Involved in clathrin-dependent endocytosis.<ref>PMID:17880279</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r7/1r79_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r79 ConSurf].
<div style="clear:both"></div>


'''Solution Structure of The C1 Domain of The Human Diacylglycerol Kinase Delta'''
==See Also==
 
*[[Diacylglycerol kinase 3D structures|Diacylglycerol kinase 3D structures]]
 
== References ==
==About this Structure==
<references/>
1R79 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R79 OCA].
__TOC__
[[Category: Diacylglycerol kinase]]
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Inoue, M.]]
[[Category: Inoue M]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Koshiba, S.]]
[[Category: Koshiba S]]
[[Category: Miyamoto, K.]]
[[Category: Miyamoto K]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Tomizawa T]]
[[Category: Tomizawa, T.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: c1 domain]]
[[Category: cystein-rich zinc binding domain]]
[[Category: diacylglycerol kinase delta]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:24:13 2008''

Latest revision as of 06:10, 17 April 2024

Solution Structure of The C1 Domain of The Human Diacylglycerol Kinase Delta

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