5b4w: Difference between revisions
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==Crystal structure of Plexin inhibitor complex== | ==Crystal structure of Plexin inhibitor complex== | ||
<StructureSection load='5b4w' size='340' side='right' caption='[[5b4w]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='5b4w' size='340' side='right'caption='[[5b4w]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5b4w]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B4W OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5b4w]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Unidentified Unidentified]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B4W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5B4W FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5b4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b4w OCA], [https://pdbe.org/5b4w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5b4w RCSB], [https://www.ebi.ac.uk/pdbsum/5b4w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5b4w ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PLXB1_HUMAN PLXB1_HUMAN] Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.<ref>PMID:12198496</ref> <ref>PMID:12196628</ref> <ref>PMID:15210733</ref> <ref>PMID:19843518</ref> <ref>PMID:20877282</ref> <ref>PMID:21912513</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5b4w" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5b4w" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Plexin 3D structures|Plexin 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Unidentified]] | ||
[[Category: | [[Category: Arimori T]] | ||
[[Category: | [[Category: Kitago Y]] | ||
[[Category: | [[Category: Matsunaga Y]] | ||
[[Category: | [[Category: Takagi J]] | ||
Latest revision as of 15:59, 8 November 2023
Crystal structure of Plexin inhibitor complex
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