5wv7: Difference between revisions
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==Crystal structure of d(CCGGGGTACCCCGG)2 at 1.4A resolution== | |||
<StructureSection load='5wv7' size='340' side='right'caption='[[5wv7]], [[Resolution|resolution]] 1.41Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5wv7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WV7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WV7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.406Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wv7 OCA], [https://pdbe.org/5wv7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wv7 RCSB], [https://www.ebi.ac.uk/pdbsum/5wv7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wv7 ProSAT]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The X-ray crystal structure of the DNA tetradecamer sequence d(CCGGGGTACCCCGG)2 is reported at 1.4 A resolution in the tetragonal space group P41212. The sequence was designed to fold as a four-way junction. However, it forms an A-type double helix in the presence of barium chloride. The metal ion could not be identified in the electron-density map. The crystallographic asymmetric unit consists of one A-type double helix with 12 base pairs per turn, in contrast to 11 base pairs per turn for canonical A-DNA. A large number of solvent molecules have been identified in both the grooves of the duplex and around the backbone phosphate groups. | |||
Crystal structure of d(CCGGGGTACCCCGG)2 at 1.4 A resolution.,Karthik S, Thirugnanasambandam A, Mandal PK, Gautham N Acta Crystallogr F Struct Biol Commun. 2017 May 1;73(Pt 5):259-265. doi:, 10.1107/S2053230X17004770. Epub 2017 Apr 26. PMID:28471357<ref>PMID:28471357</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
[[Category: | </div> | ||
[[Category: | <div class="pdbe-citations 5wv7" style="background-color:#fffaf0;"></div> | ||
[[Category: Gautham | == References == | ||
[[Category: Mandal | <references/> | ||
[[Category: Thirugnanasambandam | __TOC__ | ||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Gautham N]] | |||
[[Category: Karthik S]] | |||
[[Category: Mandal PK]] | |||
[[Category: Thirugnanasambandam A]] | |||